|
中文名
|
伊多塞班
|
|
英文名
|
Edoxaban
|
|
別名
|
依度沙班
依多沙班
伊多塞班
EDOXABAN 依度沙班
5-氯-2-吡啶-N,N-二甲基甲瞇
N1,N1'-[(1S,2R,4S)-4-(二甲氨基羰基)環(huán)己-1,2-二基]-雙[N2-(5-氯吡啶-2-基)乙二酰胺]
N-(5-氯-2-吡啶基)-N'-[(1S,2R,4S)-4-[(二甲基氨基)甲?；鵠-2-[[(4,5,6,7-四氫-5-甲基噻唑并[5,4-C]吡啶-2-基)甲酰]氨基]環(huán)己基]乙二酰胺
N-(5-氯-2-吡啶基)-N'-[(1S,2R,4S)-4-[(二甲基氨基)乙?；鵠-2-[[(4,5,6,7-四氫-5-甲基噻唑并[5,4-C]吡啶-2-基)甲酰]氨基]環(huán)己基]乙二酰胺
N-(5-氯-2-吡啶基)-N'-[(1S,2R,4S)-4-[(二甲基氨基)甲?；鵠-2-[[(4,5,6,7-四氫-5-甲基噻唑并[5,4-c]吡啶-2-基)甲酰]氨基]環(huán)己基]乙二酰胺
|
|
英文別名
|
DU-176
DU 176b
edoxaban
Edoxaban
Edoxaban base
Edoxaban(DU-176)
EthanediaMide, N1-(5-chlo...
N-(5-Chloro-2-pyridinyl)-N'-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide
EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4S)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]-
Edoxaban N-(5-Chloro-2-pyridinyl)-N'-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide
|
|
CAS
|
480449-70-5
912273-65-5
|
|
EINECS
|
1592732-453-0
|
|
化學式
|
C24H30ClN7O4S
|
|
分子量
|
548.06
|
|
密度
|
1.43
|
|
熔點
|
>213°C (dec.)
|
|
溶解度
|
Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly, Heated)
|
|
酸度系數(shù)
|
9.46±0.70(Predicted)
|
|
存儲條件
|
Hygroscopic, Refrigerator, under inert atmosphere
|
|
外觀
|
Solid
|
|
顏色
|
White to Off-White
|
